A twelve-week functional medicine protocol for women on, coming off, or recently off GLP-1 agonist medications (Ozempic, Wegovy, Mounjaro). Designed to preserve muscle mass, repair micronutrient gaps, restore energy and mood, and prevent the predictable 60-70% weight regain seen in untreated discontinuation.
A twelve-week functional medicine protocol for women on, coming off, or recently off GLP-1 agonist medications (Ozempic, Wegovy, Mounjaro). Designed to preserve muscle mass, repair micronutrient gaps, restore energy and mood, and prevent the predictable 60-70% weight regain seen in untreated discontinuation.
GLP-1 agonist medications are remarkably effective at producing weight loss. They are remarkably bad at producing the kind of body composition, mood state, and metabolic foundation that hold the loss after the medication stops.
Published data shows that without structured support, 60-70% of weight lost is regained within twelve months of stopping these medications. The reason isn't willpower — it's that the underlying physiology hasn't been rebuilt.
The Post-GLP-1 Protocol is the twelve-week intervention that changes this trajectory. It runs alongside ongoing medication for women staying on; it bridges the come-off for women tapering; it repairs the body for women already off.
We suggest a comprehensive blood panel is done by your doctor prior to starting the medication, including (where relevant) full thyroid, sex hormones, fasting insulin, HbA1c, vitamin D, B12, iron studies, ferritin, magnesium and zinc. List any results you already have — you can bring these along to your appointment. In-person clients can do a full body-composition assessment with me; these are done every 2 weeks to monitor your progress.
We work on your daily protein targets, as well as supplemental support if needed. Common supplements are magnesium glycinate, vitamin B complex, vitamin D3+K2 and omega-3, along with a hydration and electrolyte protocol.
Resistance training monitoring, gut support and sleep support.
Maintenance nutrition, maintenance lifestyle, and a training schedule to carry forward.
This protocol is appropriate for women who present with one or more of the following:
The protocol draws on published research and clinical practice across functional medicine, women's hormone health, and nutritional science. Selected references:
This protocol is delivered inside a structured programme — typically one of the six on this site. Book a free 20-minute discovery call to find the right programme for your situation.
This page cites Wilding et al. (Diabetes Obes Metab 2022) on weight regain after semaglutide is withdrawn; as summarised above, published data shows 60-70% of lost weight regained within twelve months without structured support. What the protocol works on is muscle, protein, micronutrients, sleep and a tapering plan made with your doctor. Individual results vary.
Protein comes first on the plate, resistance training is monitored through the protocol, and weeks 11-13 set up maintenance nutrition, lifestyle and a training schedule to carry forward. Your own protein target is set with you in the programme; anything medical stays with your doctor.
Any change to your dose, including tapering, is made with your prescribing doctor; Health Yourself does not set doses. What the protocol builds around the taper is protein, strength, micronutrient repair and a maintenance plan, ideally started well before you come off.
Eating less creates predictable gaps, and the ones this protocol looks for are B12, iron, magnesium, vitamin D and zinc. Food comes first, and supplements are added only if needed. Check any supplement with your doctor, especially alongside medication.
If the work fits, we map the right entry point together.